diff --git a/src/lib/defaultExtractor.js b/src/lib/defaultExtractor.js
index cde750c48..973250ea4 100644
--- a/src/lib/defaultExtractor.js
+++ b/src/lib/defaultExtractor.js
@@ -23,6 +23,47 @@ function* buildRegExps(context) {
   let separator = context.tailwindConfig.separator
   let variantGroupingEnabled = flagEnabled(context.tailwindConfig, 'variantGrouping')
 
+  let utility = regex.any([
+    // Arbitrary properties
+    /\[[^\s:'"]+:[^\s\]]+\]/,
+
+    // Utilities
+    regex.pattern([
+      // Utility Name / Group Name
+      /-?(?:\w+)/,
+
+      // Normal/Arbitrary values
+      regex.optional(
+        regex.any([
+          regex.pattern([
+            // Arbitrary values
+            /-\[[^\s:]+\]/,
+
+            // Not immediately followed by an `{[(`
+            /(?![{([]])/,
+
+            // optionally followed by an opacity modifier
+            /(?:\/[^\s'"\\$]*)?/,
+          ]),
+
+          regex.pattern([
+            // Arbitrary values
+            /-\[[^\s]+\]/,
+
+            // Not immediately followed by an `{[(`
+            /(?![{([]])/,
+
+            // optionally followed by an opacity modifier
+            /(?:\/[^\s'"\\$]*)?/,
+          ]),
+
+          // Normal values w/o quotes — may include an opacity modifier
+          /[-\/][^\s'"\\$={]*/,
+        ])
+      ),
+    ]),
+  ])
+
   yield regex.pattern([
     // Variants
     '((?=((',
@@ -38,46 +79,15 @@ function* buildRegExps(context) {
     // Important (optional)
     /!?/,
 
-    regex.any([
-      // Arbitrary properties
-      /\[[^\s:'"]+:[^\s\]]+\]/,
+    variantGroupingEnabled
+      ? regex.any([
+          // Or any of those things but grouped separated by commas
+          regex.pattern([/\(/, utility, regex.zeroOrMore([/,/, utility]), /\)/]),
 
-      // Utilities
-      regex.pattern([
-        // Utility Name / Group Name
-        variantGroupingEnabled ? /-?(?:[\w,()]+)/ : /-?(?:\w+)/,
-
-        // Normal/Arbitrary values
-        regex.optional(
-          regex.any([
-            regex.pattern([
-              // Arbitrary values
-              /-\[[^\s:]+\]/,
-
-              // Not immediately followed by an `{[(`
-              /(?![{([]])/,
-
-              // optionally followed by an opacity modifier
-              /(?:\/[^\s'"\\$]*)?/,
-            ]),
-
-            regex.pattern([
-              // Arbitrary values
-              /-\[[^\s]+\]/,
-
-              // Not immediately followed by an `{[(`
-              /(?![{([]])/,
-
-              // optionally followed by an opacity modifier
-              /(?:\/[^\s'"\\$]*)?/,
-            ]),
-
-            // Normal values w/o quotes — may include an opacity modifier
-            /[-\/][^\s'"\\$={]*/,
-          ])
-        ),
-      ]),
-    ]),
+          // Arbitrary properties, constrained utilities, arbitrary values, etc…
+          utility,
+        ])
+      : utility,
   ])
 
   // 5. Inner matches
diff --git a/tests/variant-grouping.test.js b/tests/variant-grouping.test.js
index 6e24e2c33..19978d5df 100644
--- a/tests/variant-grouping.test.js
+++ b/tests/variant-grouping.test.js
@@ -49,6 +49,41 @@ it('should be possible to group variants', () => {
   })
 })
 
+it('should be possible to group using constrained and arbitrary variants together', () => {
+  let config = {
+    experimental: 'all',
+    content: [
+      {
+        raw: html`<div
+          class="dark:[@supports(hover:hover)]:hover:[&>*]:([--potato:baked],bg-[#0088cc])"
+        ></div>`,
+      },
+    ],
+    corePlugins: { preflight: false },
+    plugins: [],
+  }
+
+  let input = css`
+    @tailwind utilities;
+  `
+
+  return run(input, config).then((result) => {
+    expect(result.css).toMatchFormattedCss(css`
+      @media (prefers-color-scheme: dark) {
+        @supports (hover: hover) {
+          .dark\:\[\@supports\(hover\:hover\)\]\:hover\:\[\&\>\*\]\:\(\[--potato\:baked\]\2c
+            bg-\[\#0088cc\]\)
+            > *:hover {
+            --tw-bg-opacity: 1;
+            background-color: rgb(0 136 204 / var(--tw-bg-opacity));
+            --potato: baked;
+          }
+        }
+      }
+    `)
+  })
+})
+
 it('should be possible to group multiple variants', () => {
   let config = {
     experimental: 'all',