diff --git a/CHANGELOG.md b/CHANGELOG.md
index a275a0134..4f6ba3b56 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -26,6 +26,7 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 
 - Vite: Ensure that updates to an imported CSS file are properly propagated after updating templates ([#17347](https://github.com/tailwindlabs/tailwindcss/pull/17347))
 - Fix class extraction followed by `(` in Pug ([#17320](https://github.com/tailwindlabs/tailwindcss/pull/17320))
+- Pre process `Slim` templates embedded in Ruby files ([#17336](https://github.com/tailwindlabs/tailwindcss/pull/17336))
 
 ### [4.0.15] - 2025-03-20
 
diff --git a/Cargo.lock b/Cargo.lock
index 21f0b3a13..31b5529a6 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -27,6 +27,21 @@ dependencies = [
  "nom",
 ]
 
+[[package]]
+name = "bit-set"
+version = "0.8.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "08807e080ed7f9d5433fa9b275196cfc35414f66a0c79d864dc51a0d825231a3"
+dependencies = [
+ "bit-vec",
+]
+
+[[package]]
+name = "bit-vec"
+version = "0.8.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "5e764a1d40d510daf35e07be9eb06e75770908c27d411ee6c92109c9840eaaf7"
+
 [[package]]
 name = "bitflags"
 version = "2.6.0"
@@ -156,6 +171,17 @@ dependencies = [
  "windows-sys 0.52.0",
 ]
 
+[[package]]
+name = "fancy-regex"
+version = "0.14.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "6e24cb5a94bcae1e5408b0effca5cd7172ea3c5755049c5f3af4cd283a165298"
+dependencies = [
+ "bit-set",
+ "regex-automata 0.4.8",
+ "regex-syntax 0.8.5",
+]
+
 [[package]]
 name = "fast-glob"
 version = "0.4.3"
@@ -538,6 +564,7 @@ dependencies = [
  "classification-macros",
  "crossbeam",
  "dunce",
+ "fancy-regex",
  "fast-glob",
  "globwalk",
  "ignore",
diff --git a/crates/oxide/Cargo.toml b/crates/oxide/Cargo.toml
index eb8b6156c..f3b67d8d7 100644
--- a/crates/oxide/Cargo.toml
+++ b/crates/oxide/Cargo.toml
@@ -19,6 +19,7 @@ bexpand = "1.2.0"
 fast-glob = "0.4.3"
 classification-macros = { path = "../classification-macros" }
 regex = "1.11.1"
+fancy-regex = "0.14.0"
 
 [dev-dependencies]
 tempfile = "3.13.0"
diff --git a/crates/oxide/src/extractor/pre_processors/ruby.rs b/crates/oxide/src/extractor/pre_processors/ruby.rs
index 180101479..edc7be49d 100644
--- a/crates/oxide/src/extractor/pre_processors/ruby.rs
+++ b/crates/oxide/src/extractor/pre_processors/ruby.rs
@@ -3,6 +3,14 @@
 use crate::cursor;
 use crate::extractor::bracket_stack;
 use crate::extractor::pre_processors::pre_processor::PreProcessor;
+use crate::pre_process_input;
+use bstr::ByteSlice;
+use fancy_regex::Regex;
+use std::sync;
+
+static TEMPLATE_REGEX: sync::LazyLock<Regex> = sync::LazyLock::new(|| {
+    Regex::new(r#"\s*(.*?)_template\s*<<[-~]?([A-Z]+?)\n([\s\S]*?)\2"#).unwrap()
+});
 
 #[derive(Debug, Default)]
 pub struct Ruby;
@@ -14,6 +22,20 @@ impl PreProcessor for Ruby {
         let mut cursor = cursor::Cursor::new(content);
         let mut bracket_stack = bracket_stack::BracketStack::default();
 
+        // Extract embedded template languages
+        // https://viewcomponent.org/guide/templates.html#interpolations
+        let content_as_str = std::str::from_utf8(content).unwrap();
+        for capture in TEMPLATE_REGEX
+            .captures_iter(content_as_str)
+            .filter_map(Result::ok)
+        {
+            let lang = capture.get(1).unwrap().as_str();
+            let body = capture.get(3).unwrap().as_str();
+            let replaced = pre_process_input(body.as_bytes(), lang);
+            result = result.replace(body, replaced);
+        }
+
+        // Ruby extraction
         while cursor.pos < len {
             // Looking for `%w` or `%W`
             if cursor.curr != b'%' && !matches!(cursor.next, b'w' | b'W') {
@@ -153,4 +175,51 @@ mod tests {
             Ruby::test_extract_contains(input, expected);
         }
     }
+
+    // https://github.com/tailwindlabs/tailwindcss/issues/17334
+    #[test]
+    fn test_embedded_slim_extraction() {
+        let input = r#"
+            class QweComponent < ApplicationComponent
+              slim_template <<~SLIM
+                button.rounded-full.bg-red-500
+                  | Some text
+                button.rounded-full(
+                  class="flex"
+                )
+                  | Some text
+              SLIM
+            end
+        "#;
+
+        Ruby::test_extract_contains(input, vec!["rounded-full", "bg-red-500", "flex"]);
+
+        // Embedded Svelte just to verify that we properly pick up the `{x}_template`
+        let input = r#"
+            class QweComponent < ApplicationComponent
+              svelte_template <<~HTML
+                  <div class:flex="true"></div>
+              HTML
+            end
+        "#;
+
+        Ruby::test_extract_contains(input, vec!["flex"]);
+
+        // Together in the same file
+        let input = r#"
+            class QweComponent < ApplicationComponent
+              slim_template <<~SLIM
+                button.z-1.z-2
+                  | Some text
+              SLIM
+            end
+
+            class QweComponent < ApplicationComponent
+              svelte_template <<~HTML
+                <div class:z-3="true"></div>
+              HTML
+            end
+        "#;
+        Ruby::test_extract_contains(input, vec!["z-1", "z-2", "z-3"]);
+    }
 }